Diseases Treated with Stem Cells and its Potential Applications

DISEASES TREATED WITH STEM CELLS

The following is a list of some of the diseases that have been treated with cord blood and other sources of similar type of stem cells (Haematopoietic Stem Cell), like bone marrow and peripheral blood. Stem cell therapies continue to change and evolve quickly.

BLOOD CANCERS

  • Acute Myelogenous Leukaemia
  • Acute Lymphoblastic Leukaemia
  • Chronic Myelogenous Leukaemia
  • Histiocytic Neoplasms
  • Other Myeloproliferative Neoplasms
  • Myelodysplastic syndrome
  • Multiple Myeloma

SOLID TUMORS

  • Hodgkin Lymphoma
  • Non-Hodgkin Lymphoma
  • Langerhans' Cell Histiocytosis
  • Neuroblastoma
  • Retinoblastoma

    NON-MALIGNANT BLOOD DISORDERS

  • Aplastic Anaemia
  • Chediak-Higashi Syndrome
  • Congenital Dyserythropoietic Anaemia
  • Diamond-Blackfan Syndrome
  • DiGeorge Syndrome
  • Evans Syndrome
  • Fanconi's Anaemia
  • Glanzmann'sThrombasthenia
  • Leukocyte Adhesion Deficiency
  • Paroxysmal Nocturnal Hemoglobinuria
  • Pure Red Cell Aplasia
  • Sickle Cell Anaemia
  • Thalassemia Major
  • Hereditary BM failure syndromes

IMMUNODEFICIENCY DISORDERS

  • Chronic Granulomatous Disease
  • Common Variable Immunodeficiency
  • Severe Combined Immune Deficiency
  • (SCID)
  • Wiskott-Aldrich Syndrome

METABOLIC DISORDERS

  • Adrenoleukodystrophy
  • Gaucher's Disease
  • Hurler Syndrome
  • Krabbe Disease
  • Metachromatic leukodystrophy
  • Osteopetrosis
  • Wolman Disease

Banking cord blood does not guarantee that the cells will provide a cure or be applicable in every situation. Use will be ultimately determined by the treating physician.

Clinical Trials

With the advancement of stem cell* research, the potential for future use of stem cell grows. Below is a list of diseases currently under Clinical Trials. These are diseases for which stem cell treatments have shown to be beneficial, but have yet to be implemented as a standard treatment. Some of these stem cell transplants only slow down the progression of the diseases, but do not produce a cure. For other diseases, the stem cell treatments may result a cure, but the optimum dosage and usage of the stem cells is still under study. For the latest information, please visit www.clinicaltrials.gov

  • Cartilage repair
  • Cerebral palsy
  • Crohn's disease
  • Diabetes Type 1
  • Ewing Sarcoma
  • Multiple Sclerosis
  • Myocardial Infarction
  • Rheumatoid Arthritis
  • Spinal cord injury

Experimental Treatments

These are randomised controlled trials conducted in a scientific laboratory involving in-vitro (test tube or cell culture) and in-vivo (animal) work. The experimental trials are in place to assist and to decide whether they have scientific merit for further development / progression to clinical trials.

  • Alzheimer's Disease
  • Amyotrophic lateral sclerosis
  • Congenital hydrocephalus
  • Huntington's Disease
  • Liver cirrhosis
  • Parkinson's Disease
  • Stroke
  • Systemic Lupus Erythematosus
  • Traumatic Brain Injury

Reference:

The above list of diseases is a compilation from the above websites and other sources such as medical literatures and journals.
(*Stem cells mentioned here comprises of other cell lines such as Epithelial and Mesenchymal stem cells & etc. The clinical trials and experimental treatments listed above may be using other lines of stem cells, and not only Haematopoietic stem cells.)


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